Research Authors

Overview

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
USERS' SCORE
Moderately Good
Based on 47 Reviews
7.8
Supplement Facts
Serving Size: 1 Veg Capsule
Amount Per Serving
%DV
5-HTP (5-hydroxytryptophan) (from Griffonia simplicifolia Extract) (seed)
50 mg
*

Top Medical Research Studies

8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
Read More
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
Read More
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.
Read More

Most Useful Reviews

7.5
Effective for weight loss
254 people found this helpful
5-hydroxytryptophan (5-HTP) is an amino acid converted in the brain to serotonin, which affects mood, behaviour, appetite, and sleep. This drug works very well for me, alleviating severe depression within 1-2 weeks. Additionally, weight loss occurred as I felt little desire to eat and experienced quick satiety. It serves as an alternative to antidepressants, but careful dosage management is crucial.
Read More
7.5
Balances mood effectively
7 people found this helpful
I've purchased this more than once, as it greatly aids during stressful work periods. 5-HTP helps stabilize serotonin production, impacting mood and emotional well-being. It reduces apathy and anxiety, assists with sleep disorders, and serves as an aid for weight loss by decreasing appetite and cravings associated with carbohydrate consumption. This property enables me to maintain a positive state without resorting to sweets.
Read More
9
Promotes weight loss
2 people found this helpful
Good dietary supplement, provides energy, diminishes appetite, and encourages weight loss. No allergies reported.
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 4 Researches
6.5
  • All Researches
8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
Read More
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
Read More
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.
Read More
We explored how obesity specialists prescribe medications including 5-HTP combined with carbidopa. Through an anonymous survey of 266 physicians, we discovered that a significant number recommended this combination for weight loss.

In a small case review, patients lost 16% of their weight with phentermine over six months and an additional 1% with 5-HTP/carbidopa. One participant even experienced a dramatic 24.4% weight loss solely from 5-HTP/carbidopa. However, further controlled studies are necessary to fully understand its effectiveness.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 47 Reviews
7.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Effective for weight loss
254 people found this helpful
5-hydroxytryptophan (5-HTP) is an amino acid converted in the brain to serotonin, which affects mood, behaviour, appetite, and sleep. This drug works very well for me, alleviating severe depression within 1-2 weeks. Additionally, weight loss occurred as I felt little desire to eat and experienced quick satiety. It serves as an alternative to antidepressants, but careful dosage management is crucial.
Read More
7.5
Balances mood effectively
7 people found this helpful
I've purchased this more than once, as it greatly aids during stressful work periods. 5-HTP helps stabilize serotonin production, impacting mood and emotional well-being. It reduces apathy and anxiety, assists with sleep disorders, and serves as an aid for weight loss by decreasing appetite and cravings associated with carbohydrate consumption. This property enables me to maintain a positive state without resorting to sweets.
Read More
9
Promotes weight loss
2 people found this helpful
Good dietary supplement, provides energy, diminishes appetite, and encourages weight loss. No allergies reported.
Read More
7.5
Gradual dosage is key
1 people found this helpful
While the drug has notable side effects initially, I manage them by splitting the capsule and gradually increasing the dosage. Its efficacy in alleviating severe depression takes 1-2 weeks. Additionally, I experience significant weight loss as my appetite decreases remarkably, making it an effective substitute for antidepressants.
Read More
9
Significant weight loss
I previously ordered this medication and am pleased with the price. It helps calm my mood and reduces cravings for sweets, contributing to significant results during my weight loss journey. I plan to reorder.
Read More

Frequently Asked Questions

9
Sleep enhancement
5-HTP improves sleep, mood, and promotes weight loss. I've been drinking it for a week and already see results. I really like it—my sleep has improved, and the compact packaging is a plus. The benefits are clear. Highly recommended! 👍
7.5
Effective for weight loss
254 people found this helpful
5-hydroxytryptophan (5-HTP) is an amino acid converted in the brain to serotonin, which affects mood, behaviour, appetite, and sleep. This drug works very well for me, alleviating severe depression within 1-2 weeks. Additionally, weight loss occurred as I felt little desire to eat and experienced quick satiety. It serves as an alternative to antidepressants, but careful dosage management is crucial.
7.5
Gradual dosage is key
1 people found this helpful
While the drug has notable side effects initially, I manage them by splitting the capsule and gradually increasing the dosage. Its efficacy in alleviating severe depression takes 1-2 weeks. Additionally, I experience significant weight loss as my appetite decreases remarkably, making it an effective substitute for antidepressants.
9
Less cravings experienced
I purchased this product to enhance my serotonin levels and have enjoyed unexpected weight loss benefits. My cravings have diminished, I fall asleep quicker, and my mood is more balanced. The small capsules are flavourless, and I'm pleased with the positive effects.
9
Mood improved significantly
I've been taking this supplement for about a month, and it has calmed my reactions to frustrating situations while also improving my mood and sleep. The effect on weight loss is very noticeable, as my appetite has decreased significantly, especially for sweets.
7.5
Balances mood effectively
7 people found this helpful
I've purchased this more than once, as it greatly aids during stressful work periods. 5-HTP helps stabilize serotonin production, impacting mood and emotional well-being. It reduces apathy and anxiety, assists with sleep disorders, and serves as an aid for weight loss by decreasing appetite and cravings associated with carbohydrate consumption. This property enables me to maintain a positive state without resorting to sweets.
7.5
Increased satiety levels
This amino acid increases satiety levels, contributing to weight loss. While fat burning can boost hormone production, leading to hunger, 5-HTP counters this effect by suppressing appetite. I tested it and can vouch for its effectiveness.
7.5
Quality improves mood
5-HTP from NOW Foods is renowned for its quality, used primarily for enhancing serotonin production, effectively improving mood and alleviating depression. It aids in sleep quality and reduces stress while assisting with weight loss by suppressing appetite. Regular use provides positive mood benefits, and it is recommended to take one capsule daily with food to mitigate any side effects.
7.5
Useful for stress relief
47 people found this helpful
A must-have for neurotics and those struggling with depression. Constant stress had me considering antidepressants, but a course of 5-HTP before bedtime yielded results within days, demonstrating cumulative benefits. While stressors persist, my reaction is less intense, and I now avoid stress-induced eating, contributing to my weight loss. Initially concerned about my sensitive stomach, I found 5-HTP agreeable, with no impact on my migraine frequency.
9
Calms nerves
Excellent! It helps with weight loss, calms my nerves, and reduces the desire to overeat!
9
Lost 10 kg achieved
I found this remedy effective for falling asleep and experiencing weight loss. I took it 30 minutes before bedtime, leading to a restful night. I managed to lose 10 kg in a month while monitoring my calorie intake.
9
Discourages cravings for sweets
This product works well! I take 5-HTP during stressful periods, and even on a low dosage, it helps me manage stress and reduces cravings for sweets. This has greatly contributed to weight loss, as I now eat only when I'm genuinely hungry. I recommend it, especially taken in the morning.
6
Reduces appetite effectively
3 people found this helpful
5-Hydroxytryptophan (5-HTP) is a precursor of serotonin, beneficial for various conditions including mood enhancement, appetite suppression, and sleep regulation. It offers a milder alternative to traditional antidepressants and is noted for its ability to improve mood, decrease anxiety, and assist in managing appetite. Users should be cautious about its compatibility with other medications.
7.5
Supports appetite control
4 people found this helpful
5-HTP effectively reduces excessive carbohydrate consumption and supports weight loss. Historical research indicates that it significantly diminishes food intake and prevents weight gain, particularly in mice genetically predisposed to obesity. For optimal results, it is advisable to take 5-HTP around mealtimes, ideally before meals, to enhance sleep quality.
We explored how a unique sublingual spray formulation containing 5-hydroxytryptophan (5-HTP) influences appetite in overweight women. In our two-month study, 27 participants were divided into treatment and placebo groups to assess daily appetite sensations. While the findings indicate that 5-HTP may contribute positively to appetite control, there was no significant weight loss noted in participants. This suggests that while it could complement weight loss efforts, it may not directly cause weight reduction.
We explored how obesity specialists prescribe medications including 5-HTP combined with carbidopa. Through an anonymous survey of 266 physicians, we discovered that a significant number recommended this combination for weight loss.

In a small case review, patients lost 16% of their weight with phentermine over six months and an additional 1% with 5-HTP/carbidopa. One participant even experienced a dramatic 24.4% weight loss solely from 5-HTP/carbidopa. However, further controlled studies are necessary to fully understand its effectiveness.
8
5-HTP aids in weight loss
We looked into how 5-hydroxytryptophan (5-HTP) functions in aiding weight loss among obese individuals. In a well-structured study, 20 participants were split into two groups—one received 5-HTP and the other a placebo. Notably, over two 6-week phases, those taking 5-HTP reported significant weight loss, reduced carb intake, and felt fuller quicker.

These findings suggest that 5-HTP could be a safe option for supporting weight management without the immediate need for dietary restrictions.
7
5-HTP promotes weight loss in rats
We investigated the effects of 5-hydroxytryptophan (5-HTP) on body weight and metabolic functions in spontaneously hypertensive rats over a 12-day period.

Our findings revealed that rats receiving 5-HTP experienced significant reductions in body weight, food and water intake, and lower blood pressure compared to the control group.

This suggests that enhancing serotonin production in the brain may lead to weight loss and metabolic changes. However, these results are preliminary and based on animal studies, so further research is needed to confirm similar effects in humans.

References

  1. Rondanelli M, Klersy C, Iadarola P, Monteferrario F, Opizzi A. Satiety and amino-acid profile in overweight women after a new treatment using a natural plant extract sublingual spray formulation. Int J Obes (Lond). 2009;33:1174. 10.1038/ijo.2009.155
  2. Hendricks EJ, Rothman RB, Greenway FL. How physician obesity specialists use drugs to treat obesity. Obesity (Silver Spring). 2009;17:1730. 10.1038/oby.2009.69
  3. Cangiano C, Ceci F, Cascino A, Del Ben M, Laviano A, et al. Eating behavior and adherence to dietary prescriptions in obese adult subjects treated with 5-hydroxytryptophan. Am J Clin Nutr. 1992;56:863.
  4. Itskovitz HD, Werber JL, Sheridan AM, Brewer TF, Stier CT. 5-Hydroxytryptophan and carbidopa in spontaneously hypertensive rats. J Hypertens. 1989;7:311.
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